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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 75-year-old man with a medical history significant for hypertension, diabetes mellitus, and erectile dysfunction returns for follow-up. He currently takes benazepril, glipizide, and sildenafil as needed. He is in the clinic today with symptoms of depression. The physician wants to start an antidepressant that will have a minimal effect on the patient's erectile dysfunction. Which of the following agents would be the best recommendation?

A) Desipramine
B) Venlafaxine
C) Fluoxetine
D) Bupropion

2. A patient with diabetic ketoacidosis is receiving 0.9% NaCl, with potassium chloride 20 mEq/L, at 200 mL/h, and regular insulin 8 units/h, intravenously. After 8 hours, the blood glucose is
250 mg/dL and the anion gap is elevated. At this point, which of the following is the most appropriate therapy?

A) Continue the current insulin and fluid therapy.
B) Discontinue the insulin and maintain current fluids.
C) Convert to subcutaneous regular insulin and reduce fluids to a keep-vein-open rate.
D) Continue the insulin infusion rate and change to dextrose-containing fluids.

3. A 40-year-old transplant recipient who is receiving cyclosporine develops seizures requiring anticonvulsant therapy. Because a drug interaction is likely to occur between cyclosporine and phenytoin, the pharmacotherapy specialist suggests that the resident do which of the following?

A) Increase the phenytoin dose.
B) Decrease the phenytoin dose.
C) Increase the cyclosporine dose.
D) Decrease the cyclosporine dose.

4. To correct the development of metabolic acidosis in patients receiving standard TPN solutions, which of the following is the best therapeutic intervention?

A) Hyperventilate the patient to produce hypocapnia.
B) Decrease the chloride and increase the acetate.
C) Decrease the potassium and increase the calcium.
D) Decrease the phosphate and add bicarbonate.

5. Using a new assay, the following readings for Drug X concentration in a blood sample are obtained: 45 ng/mL, 43 ng/mL, 45 ng/mL, 44 ng/mL, 45 ng/mL, and 45 ng/mL. The true concentration of the drug was reported as 65 ng/mL using the gold-standard assay.
On the basis of these data, the new assay should be characterized in which of the following categories?

A) Neither accurate nor precise
B) Precise but not accurate
C) Accurate but not precise
D) Both accurate and precise

Solutions: