Authentic BPS-Pharmacotherapy Dumps With 100% Passing Rate Practice Tests Dumps
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NEW QUESTION 86
A pharmacotherapy specialist has been asked to provide information on the incidence of a particular side effect for a drug that has now been on the U.S. market for 5 years. The only information available comes from the FDA's MedWatch program. The apparent incidence of a given adverse effect, as determined from the MedWatch database, is likely to be which of the following?
- A. Reliable because the data are accumulated in cooperation with the pharmaceutical industry
- B. Unreliable because the voluntary nature of reporting makes numerator data questionable
- C. Reliable because healthcare institutions such as hospitals are mandated to report all adverse drug events to the FDA
- D. Unreliable because reporting healthcare providers usually fail to establish a temporal relationship
Answer: C
NEW QUESTION 87
An 18-year-old patient presents with abrasions on the hands, knees, and shoulder from a recent bicycle accident. Gram-staining of surgical incision and drainage specimens reveals Gram positive cocci in chains. The patient has necrotizing fasciitis and develops bronchospasms after being given penicillin. Which intravenous antibiotic would be best to use in place of penicillin?
- A. Ciprofloxacin
- B. Clindamycin
- C. Sulfamethoxazole/trimethoprim
- D. Ceftriaxone
Answer: B
NEW QUESTION 88
A 21-year-old patient with leukemia is admitted to the hospital with a temperature of 38.9°C and a nonproductive cough 8 days after induction chemotherapy completion. Laboratory tests show a WBC count of 1,000 cells/ul (10% segmented neutrophils, 0% bands, and 90% lymphocytes) and a platelet count of 60,000 cells/uL. Chest X-ray reveals a small left lower lobe infiltrate. Blood, urine, and sputum cultures are obtained. What should be the recommendation for initial management?
- A. Initiate fluconazole, vancomycin, and imipenem.
- B. Initiate cefepime, Vancomycin, and tobramycin.
- C. Initiate amphotericin, ceftazidime, and gentamicin.
- D. Hold antibiotics until Culture results are available.
Answer: B
NEW QUESTION 89
A 74-year-old man has been diagnosed with acute bacterial prostatitis. He has no known drug allergies. Which of the following is the optimal therapy duration with levofloxacin 500 mg daily?
- A. 3-5 days
- B. 2-4 Weeks
- C. 6-8 Weeks
- D. 7-10 days
Answer: B
NEW QUESTION 90
A population study of gentamicin pharmacokinetics in 425 neonates reported the following correlation by least-squares linear regression between gestational age and gentamicin clearance:
r2 = 0.35, p = 0.0001. Which of the following is the most appropriate interpretation of these data?
- A. A significant correlation exists between gestational age and gentamicin clearance, with gestational age accounting for 65% of the variability in gentamicin clearance.
- B. A significant correlation exists between gestational age and gentamicin clearance, with gestational age accounting for 59% of the variability of gentamicin clearance.
- C. A correlation coefficient of less than 0.8 essentially means no significant relationship exists between gestational age and gentamicin clearance in neonates.
- D. A significant correlation exists between gestational age of newborns and gentamicin clearance, but gestational age accounts for only 35% of the variability in clearance.
Answer: D
NEW QUESTION 91
A pharmacotherapy specialist is interpreting a published paper describing a randomized controlled, double-bling study that was conducted to evaluate the effects of antihistamines on the failure rate of treatment of otitis media in children. In the study, 250 children received antihistamines and 264 did not. All children received appropriate antibiotic therapy. Treatment failures occurred in four (1.6%) of the children who received antihistamines and in 13 (4.9%) of those who did not. The difference is statistically significant (p<0.05, chi-square). Which of the following statements about these result is appropriate?
- A. The sample size is inadequate to allow clinical conclusions.
- B. Knowledge of the rate and severity of adverse event in the study is needed to allow a therapeutic decision.
- C. Antihistamines should be administered to all children with otitis media who meet study entry criteria.
- D. Chi-square is not the appropriate statistical test.
Answer: D
NEW QUESTION 92
A 65-year-old Woman presents with complaints of Worsening incontinence associated with sneezing and coughing, as well as itching in the genital area. Physical examination reveals some vaginal atrophy. A pad test is positive, post void residuals average 5 mL, and urinalysis is normal. Which of the following is the best treatment option for this patient?
- A. Tamsulosin
- B. Vaginal estrogen cream
- C. Tolterodine
- D. Bethanechol
Answer: B
NEW QUESTION 93
A 28 year old patient presents to a physician and reports persistent nasal discharge and facial tenderness for the past 15 days. The patient has no known drug allergies. Which recommendation would be best for treating this acute sinusitis?
- A. No antimicrobial indicated at this time
- B. Amoxicillin/clavulanate acid
- C. Azithromycin
- D. Sulfamethoxazole/trimethoprim
Answer: B
NEW QUESTION 94
A patient with a COPD exacerbation is treated with prednisone 40 mg daily for one week with improvement. To discontinue the prednisone, the most appropriate procedure would be which of the following?
- A. Stopping prednisone administration without dose tapering.
- B. Reducing the daily prednisone dose by 50% every day until the patient is off the drug.
- C. Reducing the daily prednisone dose by 50% every other day until it is down to 10 mg daily, then reducing it by 25% every other day until the patient is off the drug.
- D. Reducing the daily prednisone dose by 25% every day until the patient is off the drug.
Answer: A
NEW QUESTION 95
A 58-year-old woman presents to the emergency department of a small rural hospital with recurrent chest pain that is unrelieved by three sublingual nitroglycerin tablets. Initial evaluation of her ECG and cardiac enzymes are consistent with non-STEMI. The woman is admitted for observation and given aspirin. Which of the following should be added to this patient's regimen to reduce her risk of death, MI, and recurrent ischemia?
- A. Oral warfarin
- B. Subcutaneous heparin
- C. Intravenous t-PA
- D. Subcutaneous enoxaparin
Answer: D
NEW QUESTION 96
A patient asks for advice relative to an herbal supplement to treat heart failure. The patient is currently NYHA Class III (LVEF 25%) and is adherent to medications, which include digoxin
0.25 mg daily, furosemide 40 mg daily, lisinopril 10 mg daily, carvedilol 6.25 mg twice daily, potassium 20 mEq daily, and simvastatin 40 mg nightly.
The patient has BP of 120/78 mm Hg, HR of 60 bpm, 9 cm JVD, 2+ pitting edema, and has experienced a 2.3 kg weight gain in last 2 days. All laboratory values are within normal limits.
Based on the following information, what is the most appropriate suggestion for the patient?
- A. Coenzyme Q10
- B. Omega-3-fatty acid
- C. L-Carnitine
- D. Avoidance of dietary supplements
Answer: B
NEW QUESTION 97
A 53-year-old patient with an 8-year history of diabetes is currently taking glipizide 10 mg twice daily before breakfast and supper. The patient weighs 85 kg and reports a 4.5 kg weight gain in the last year. Laboratory results are:
Creatinine: 1.2 mg/dL
A1C: 8.5%
What is the most appropriate recommendation at this time for improved diabetes control?
- A. Change glipizide to insulin.
- B. Change glipizide to metformin.
- C. Increase glipizide to 20 mg twice daily.
- D. Continue with glipizide and add metformin.
Answer: B
NEW QUESTION 98
A 46-year-old patient begins treatment with allopurinol 300 mg daily following the onset of an acute gout attack due to elevated uric acid.
The patient's other medications are:
* Cyclosporine 800 mg daily
* Prednisone 20 mg daily
* Azathioprine 100 mg daily
* Nifedipine extended release 90 mg daily
Several days later there was an observed decrease in the patient's WBC count. Which drug interaction with allopurinol is most likely to account for this change?
- A. Azathioprine
- B. Prednisone
- C. Cyclosporine
- D. Nifedipine
Answer: C
NEW QUESTION 99
A clinical trial is being designed to evaluate the efficacy of an intermediate-acting niacin preparation in a population with regard to amelioration of coronary artery disease risk.
Bioethical considerations would restrict recruitment of subjects with poorly controlled diabetes mellitus, recent gastroduodenal ulcer disease, or hyperuricemia. Which principle would consider these patients to be ineligible for enrollment?
- A. Autonomy
- B. Beneficence
- C. Equipoise
- D. Justice
Answer: A
NEW QUESTION 100
A 40-year-old transplant recipient who is receiving cyclosporine develops seizures requiring anticonvulsant therapy. Because a drug interaction is likely to occur between cyclosporine and phenytoin, the pharmacotherapy specialist suggests that the resident do which of the following?
- A. Decrease the phenytoin dose.
- B. Decrease the cyclosporine dose.
- C. Increase the cyclosporine dose.
- D. Increase the phenytoin dose.
Answer: C
NEW QUESTION 101
A patient presents a first-time prescription for exenatide subcutaneously twice daily. Which of the following information should the pharmacotherapy specialist present during patient counseling?
- A. The most common side effect is nausea, which usually decreases over time.
- B. Dose size should be adjusted according to the size of each meal.
- C. The drug should be discarded 60 days after first use, even if some remains in the pen.
- D. The drug should be taken within 60 minutes after eating the morning and evening meals.
Answer: D
NEW QUESTION 102
Investigators studying the relative nephrotoxicity of two aminoglycosides selected their sample size to detect a reduction in toxicity of 10%. Which of the following is the power of this study if the probability of falsely rejecting the null hypothesis is 0.05 and the probability of falsely accepting the null hypothesis is 0.20?
- A. 0.05
- B. 0.95
- C. 0.10
- D. 0.80
Answer: D
NEW QUESTION 103
A 65-year-old man presents to the internal medicine clinic with decreased exercise tolerance, lower extremity edema, and shortness of breath.
He has a history of diastolic dysfunction (ejection fraction of 60%) and hypertension; BP =
150/90 mm Hg, HR = 86 bpm.
Current medications include digoxin 125 mcg daily, furosemide 40 mg daily, enalapril 10 mg twice daily, aspirin 325 mg daily, and potassium 10 mEq twice daily. The digoxin concentration is 0.4 ng/mL.
After resolution of this exacerbation, which of the following should the pharmacotherapy specialist recommend to the internist regarding this patient's maintenance drug therapy?
- A. Discontinue digoxin and add amlodipine.
- B. Increase digoxin.
- C. Increase furosemide.
- D. Discontinue digoxin and add metoprolol.
Answer: D
NEW QUESTION 104
A 50-kg 15-year-old female patient presents to the emergency department 6 hours after ingesting 100 ferrous sulfate tablets, each containing 325 mg. A pregnancy test is negative, and flat plate radiography of the abdomen demonstrates many tablets in the stomach and throughout the small intestine. The patient is intermittently vomiting, with no tablets recovered in the emesis. The patient is otherwise asymptomatic and stable. Which of the following forms of gastrointestinal decontamination should be recommended?
- A. Gastric lavage
- B. Whole bowel irrigation
- C. Ipecac syrup administration
- D. Activated charcoal administration
Answer: B
NEW QUESTION 105
A 60-year-old man is admitted to the CCU with an acute anterior wall Ml. Therapy with amiodarone is initiated. The man's concurrent medications include Warfarin, furosemide, and enalapril. Which of the following baseline laboratory land clinical data, in addition to thyroid and liver function tests, should be obtained prior to initiation of amiodarone therapy in this patient?
- A. FEV1 and baseline electroencephalogram
- B. Spirometry and 24-hour urine for creatinine clearance
- C. Chest X-ray
- D. Fasting blood glucose
Answer: A
NEW QUESTION 106
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